I really don't know what to do...?

I am a 33 years old and I have been unemployed since 2001 after finding out I was HIV positive. At the time i was also laid off from a telemarketing job i did for many years due to downsizing. I went on a public istant program called HASA that focuses on helping people living with HIV/AIDS. They pay my rent in full, give me $172.00 bi-weekly, and $ 200.00 in food stamps, I also get medicaid. For years i have been made to feel guilty by society about living on welfare, and everyone always seems to be bragging about work and how wonderful it is to work. For one year now my niece has been living with me. because she is in foster care and her mom (my sister) can't take care of her. I took it upon myself to take care of my niece and be a stay at home foster parent. I get paid $1000 and something monthly in addition to the money from HASA to take care of my niece, but she is 13 years old and in middle school and i feel probably more quilty now about being unemployed than before. I also suffer from depression, i have no friends, and my life seems to have been stuck for many many years. The fantasy of returning back to work and having the energy, and pride of a working man is in me, but to be quite honest i've been out of the game for too long and don't know where to start. I am also scarred to lose my public istance benefits if i return to work, for these are tough times and HASA is paying my rent entirely. I think if i return back to work it would have to be part time, because of the obvious reasons stated above. I am trying to raise my niece and i'm doing it alone, she has ADHD and it feels as if i need to always be watching her. I am constantly cooking, cleaning, taking her to her appointments, dealing with case workers for home visits, shopping, laundry, and it sometimes seems as if i am too busy and tired to get a "real job"...can someone please give me some advice?